GHK-Cu
Also referenced as: Array
Neutral technical record and index of the peer-reviewed literature referencing GHK-Cu. For research use only — no human or veterinary use, benefit, or dosing information is provided.
Identity
| PubChem CID | 139035031 |
|---|---|
| Molecular formula | C14H21CuN6O4- |
| Molecular weight | 400.90 g/mol |
| InChIKey | LREZPQNYQZAPJC-ACMTZBLWSA-L |
What it is
GHK-Cu is the copper(II) complex of the human tripeptide glycyl-L-histidyl-L-lysine (GHK). It is classed as a copper-binding tripeptide. It is supplied as lyophilized material for research use only.
Mechanism (technical)
GHK-Cu has been studied for its association with copper homeostasis, oxidative-stress pathways, and modulation of gene expression. Preclinical work has examined its influence on inflammation and fibrosis markers, including a study implicating peroxiredoxin 6 in a silicosis model. These mechanisms are described across review and animal literature.
Peer-reviewed literature
5 studies indexed · 3 animal · 1 in-vitro · 1 review. Listed neutrally; outcome studies are indexed, not endorsed.
- GHK-Cu(2+) attenuates lung inflammation/fibrosis in silicosis via peroxiredoxin 6Bian Y, et al. · 2024 · Redox Biol · animal · animal
- Liposomes as Carriers of GHK-Cu Tripeptide for Cosmetic ApplicationDymek M, et al. · 2023 · Pharmaceutics · in-vitro · in-vitro
- GHK-Cu protective effects in bleomycin-induced pulmonary fibrosisMa WH, et al. · 2020 · Life Sci · animal · animal
- GHK-Cu(II) transiently improved healing outcome in a rat model of ACL reconstructionFu SC, et al. · 2015 · J Orthop Res · animal · animal
- The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of agingPickart L, et al. · 2012 · Oxid Med Cell Longev · review · review
For research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or dietary supplement. Sold to qualified researchers for laboratory research purposes only.