Thymosin Alpha-1
Also referenced as: Array
Neutral technical record and index of the peer-reviewed literature referencing Thymosin Alpha-1. For research use only — no human or veterinary use, benefit, or dosing information is provided.
Identity
| PubChem CID | 16130571 |
|---|---|
| CAS number | 62304-98-7 |
| Molecular formula | C129H215N33O55 |
| Molecular weight | 3108.3 g/mol |
| InChIKey | NZVYCXVTEHPMHE-ZSUJOUNUSA-N |
What it is
Thymosin Alpha-1 (thymalfasin) is a synthetic 28-amino-acid peptide corresponding to a naturally occurring thymic peptide. It is classed as an immunomodulatory thymic peptide. It is supplied as lyophilized material for research use only.
Mechanism (technical)
Thymosin Alpha-1 has been studied for its association with T-cell maturation and immune modulation, including effects on lymphocyte counts and immune parameters. These mechanisms have been investigated as an adjunct to standard care in infectious and oncologic settings. The immunorestorative rationale is described across the indexed trials.
Peer-reviewed literature
5 studies indexed · 5 human. Listed neutrally; outcome studies are indexed, not endorsed.
- Thymalfasin pilot trial in hospitalized COVID-19 with lymphocytopeniaShehadeh F, et al. · 2023 · J Infect Dis · clinical trial · human
- Efficacy of thymosin alpha 1 for severe sepsis (ETASS): multicenter RCTWu J, et al. · 2013 · Crit Care · RCT · human
- Thymosin alpha 1, interferon alfa, or both with dacarbazine in metastatic melanoma: RCTMaio M, et al. · 2010 · J Clin Oncol · RCT · human
- Thymosin alpha-1 in Japanese patients with chronic hepatitis B: RCTIino S, et al. · 2005 · J Viral Hepat · RCT · human
- Immunorestorative properties of thymosin-alpha 1 in lung cancer: RCTSchulof RS, et al. · 1985 · J Biol Response Mod · RCT · human
For research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or dietary supplement. Sold to qualified researchers for laboratory research purposes only.