TB-500
Also referenced as: Array
Neutral technical record and index of the peer-reviewed literature referencing TB-500. For research use only — no human or veterinary use, benefit, or dosing information is provided.
Identity
| PubChem CID | 45382195 |
|---|---|
| Molecular formula | C212H350N56O78S |
| Molecular weight | 4963 g/mol |
| InChIKey | UGPMCIBIHRSCBV-UHFFFAOYSA-N |
What it is
TB-500 is a synthetic peptide corresponding to an active region of thymosin beta-4, an actin-binding protein. It is classed as a thymosin beta-4-related regenerative peptide. It is supplied as lyophilized material for research use only.
Mechanism (technical)
TB-500 and thymosin beta-4 have been studied for actin binding and association with cell migration, angiogenesis, and tissue-repair signaling. These mechanisms have been investigated in preclinical wound and injury models. The molecular pathways are described across review and animal literature.
Peer-reviewed literature
5 studies indexed · 3 animal · 2 review. Listed neutrally; outcome studies are indexed, not endorsed.
- Tb4-Engineered ADSC Extracellular Vesicles ... for Diabetic Wound HealingDing Y, et al. · 2025 · Adv Sci · animal · animal
- Thymosin beta-4 - a potential tool in healing middle ear lesions in adult mammalsBako P, et al. · 2023 · Int Immunopharmacol · animal · animal
- Thymosin beta4 Promotes Dermal HealingKleinman HK, Sosne G · 2016 · Vitam Horm · review · review
- Thymosin beta4: a multi-functional regenerative peptideGoldstein AL, et al. · 2012 · Expert Opin Biol Ther · review · review
- Thymosin beta 4 promotes corneal wound healing and decreases inflammation after alkali injurySosne G, et al. · 2002 · Exp Eye Res · animal · animal
For research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or dietary supplement. Sold to qualified researchers for laboratory research purposes only.