Ipamorelin
Neutral technical record and index of the peer-reviewed literature referencing Ipamorelin. For research use only — no human or veterinary use, benefit, or dosing information is provided.
Identity
| PubChem CID | 9831659 |
|---|---|
| CAS number | 170851-70-4 |
| Molecular formula | C38H49N9O5 |
| Molecular weight | 711.9 g/mol |
| InChIKey | NEHWBYHLYZGBNO-BVEPWEIPSA-N |
What it is
Ipamorelin is a synthetic pentapeptide classed as a selective growth hormone secretagogue. It acts as a ghrelin/growth hormone secretagogue receptor agonist. It is supplied as lyophilized material for research use only.
Mechanism (technical)
Ipamorelin has been studied for its action on the growth hormone secretagogue receptor to stimulate growth hormone release, with foundational preclinical work characterizing its selectivity relative to other secretagogues. Its downstream association with IGF-1 has been examined in animal models. Gastrointestinal motility signaling has also been investigated in ileus models.
Peer-reviewed literature
5 studies indexed · 1 human · 4 animal. Listed neutrally; outcome studies are indexed, not endorsed.
- RCT of ipamorelin for postoperative ileus in bowel-resection patientsBeck DE, et al. · 2014 · Int J Colorectal Dis · RCT · human
- Efficacy of ipamorelin in a rodent model of postoperative ileusVenkova K, et al. · 2009 · J Pharmacol Exp Ther · animal · animal
- Ipamorelin and GHRP-6 increase bone mineral content in adult female ratsSvensson J, et al. · 2000 · J Endocrinol · animal · animal
- Ipamorelin induces longitudinal bone growth in ratsJohansen PB, et al. · 1999 · Growth Horm IGF Res · animal · animal
- Ipamorelin, the first selective growth hormone secretagogueRaun K, et al. · 1998 · Eur J Endocrinol · animal · animal
For research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or dietary supplement. Sold to qualified researchers for laboratory research purposes only.