Epithalon
Also referenced as: Array
Neutral technical record and index of the peer-reviewed literature referencing Epithalon. For research use only — no human or veterinary use, benefit, or dosing information is provided.

Identity
| PubChem CID | 219042 |
|---|---|
| CAS number | 307297-39-8 |
| Molecular formula | C14H22N4O9 |
| Molecular weight | 390.35 g/mol |
| InChIKey | HGHOBRRUMWJWCU-FXQIFTODSA-N |
What it is
Epithalon (also written epitalon; AEDG peptide) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on a pineal gland peptide. It is classed as a short synthetic peptide. It is supplied as lyophilized material for research use only.
Mechanism (technical)
Epithalon has been studied in in-vitro systems for its association with telomerase activity and telomere length in human somatic cells. Additional in-vitro work has investigated its influence on gene expression related to neurogenesis and on antioxidant and cell-migration endpoints. The mechanistic literature is primarily cell-based.
Peer-reviewed literature
4 studies indexed · 4 in-vitro. Listed neutrally; outcome studies are indexed, not endorsed.
- Epitalon enhances delayed wound healing in an in-vitro diabetic retinopathy modelGatta M, et al. · 2025 · Stem Cell Rev Rep · in-vitro · in-vitro
- Overview of Epitalon - pineal tetrapeptide (review)Araj SK, et al. · 2025 · Int J Mol Sci · review · in-vitro
- AEDG peptide (epitalon) stimulates gene expression during neurogenesisKhavinson V, et al. · 2020 · Molecules · in-vitro · in-vitro
- Epithalon induces telomerase activity and telomere elongation in human somatic cellsKhavinson VKh, et al. · 2003 · Bull Exp Biol Med · in-vitro · in-vitro
For research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or dietary supplement. Sold to qualified researchers for laboratory research purposes only.